Join Thea Stilton and the Thea Sisters on an adventure packed with mystery and friendship! The Thea Sisters are taking a road trip across America along Route 66! They stop in Chicago, St. Louis, and other cities on the way to San Jose. Their friend, Ali, is a programmer and she has a chance to have her project turned into a real video game. But while they are on the road someone wipes her computer and all of her hard work is lost! Can the mouselets figure out what happened and help her get it all back?